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With ASU affiliation:

  • M. Mondal, R. Liao, C. Nazaroff, A. Samuel, and J. Guo*. “Highly multiplexed single-cell in situ RNA and DNA analysis with bioorthogonal cleavable fluorescent oligonucleotide probes” Chem. Sci. In press.
  • L. Xiao, and J. Guo*. “Single-cell in situ RNA analysis with switchable fluorescent oligonucleotides” Front. Cell Dev. Biol. In press.
  • M. Mondal, R. Liao, and J. Guo*. “Highly multiplexed single-cell protein analysis” Chem. Eur. J. In press.
  • E. N. Tóth, A. Lohith, M. Mondal, and J. Guo, A. Fukamizu, N. Pourmand*. “Single-cell nanobiopsy reveals compartmentalization of mRNAs within neuronal cells” J Biol Chem, In press.
  • M. Mondal, R. Liao, L. Xiao, T. Eno, and J. Guo*. “Highly multiplexed single cell in situ protein analysis with cleavable fluorescent antibodies” Angew Chem Int Ed, 2017, 56: 2636-2639.
  • Highlighted as hot paper in Angew Chem Int Ed
  • Highlighted in ACS Chem Biol
  • M. Mondal, and J. Guo*. “Comet-FISH for ultra-sensitive strand-specific detection of DNA damage in single cells”Method Emzymol. 2017, 591: 83-95.
  • L. Xiao, and J. Guo*. “Multiplexed single-cell in situ RNA analysis by reiterative hybridization” Analytical Methods, 2015, 7: 7290-7295.

Prior to ASU:

  • J. Guo, P. C. Hanawalt, and G. Spivak*. “Comet-FISH with strand-specific probes reveals transcription-coupled repair of 8-oxoGuanine in human cells” Nucleic Acids Res, 2013, 41: 7700-7712.
  • J. Guo, J. Ju and N. J. Turro*. “Fluorescent hybridization probes for nucleic acid detection” Anal Bioanal Chem, 2012, 402:3115-3125.


  • S. Wang, J. Guo, T. Ono and E. T. Kool*. “DNA polyfluorophores for real-time multicolor tracking of dynamic biological systems” Angew Chem Int Ed, 2012, 51:7176-7180.
  • C. Qiu, S. Kumar, J. Guo, J. Lu, S. Shi, S. Kalachikov, J. Russo, A. Naini, E. Schon and J. Ju*. “Mitochondrial SNP genotyping by MALDI-TOF mass spectrometry using cleavable biotinylated dideoxynucleotides” Anal Biochem, 2012, 427:202-210.
  • C. Qiu, S. Kumar, J. Guo, L. Yu, W. Guo, S. Shi, J. Russo and J. Ju*. “Design and synthesis of cleavable biotinylated dideoxynucleotides for DNA sequencing by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry” Anal Biochem, 2012, 427:193-201.
  • J. Guo, S. Wang, N. Dai, Y. N. Teo and E. T. Kool*. “Multispectral labeling of antibodies with polyfluorophores on a DNA backbone and application in cellular imaging” PNAS, 2011, 108: 3493-3498.
  • Highlighted in Nat Methods


  • N. Dai, J. Guo, Y. N. Teo and E. T. Kool*. “Protease probes built from DNA: multispectral fluorescent DNA–peptide conjugates as caspase sensors” Angew Chem Int Ed, 2011, 50:5105-5109.
  • Highlighted as hot paper in Angew Chem Int Ed
  • J. Guo, L. Yu, N. J. Turro* and J. Ju*. “An integrated system for DNA sequencing by synthesis using novel nucleotide analogues” Acc Chem Res, 2010, 43: 551-563.


  • J. Guo, N. Xu, Z. Li, S. Zhang, J. Wu, D. H. Kim, M. S. Marma, Q. Meng, H. Cao, X. Li, S. Shi, L. Yu, S. Kalachikov, J. Russo, N. J. Turro* and J. Ju*. “Four-color DNA sequencing with 3’-O-modified nucleotide reversible terminators and chemically cleavable fluorescent dideoxynucleotides” PNAS, 2008, 105: 9145-9150.
  • Highlighted in PNAS, ranked 50 most read PNAS papers
  • Z. Wang, X. Xu*, Y. Chen, S. Zhou, N. Kong, J. Guo, H. Liu and C. Shi. “Characteristics of the ZnxMg1-xO films grown by electrophoresis method” Acta Physica Sinica, 2004, 53: 3924-3928.
  1. P. C. Hanawalt, G. Spivak and J. Guo. “Strand specific probes for analyzing very low levels of DNA damage within genes in single cells” Patent filed. 
  2. J. Ju, D. H. Kim, J. Guo, Q. Meng, Z. Li and H. Cao. “DNA sequencing with non-fluorescent nucleotide reversible terminators and cleavable label modified nucleotide terminatorsPCT Int. Appl. 2009, WO 2009054922.
  3. J. Ju, H. Cao, Z. Li, Q. Meng, J. Guo, S. Zhang and L. Yu. “Design and synthesis of labile azido linkers for conjugation of fluorescent dyes to nucleotides for use as reversible terminators in DNA sequencing by synthesis” PCT Int. Appl. 2009, WO 2009051807.

ASU Department of Chemistry & Biochemistry

Arizona State University